Fig. 6. The COD removal and the release of inorganic and nitrogen organic (Norg) forms after a 4 h electrolysis of IF and CF. Experimental conditions: [IF] = [CF] = 0.19 mM, initial pH = 6.5, current density = 16 mA cm−2, T = 25 °C. Ct denotes a maximum amount of appropriate AMN-107 released from drug molecule under experimental conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide
Fig. 7. Variation in the concentration of the analyzed cytostatic drugs and the main intermediate products detected during electrolysis.Figure optionsDownload full-size imageDownload as PowerPoint slide
The electrochemical oxidation of two cytostatic drugs IF and CF in a one compartment reactor with the BDD electrode is presented. The obtained results indicate that the boron-doped diamond electrode is quite efficient with regard to the degradation of both analyzed drugs. The typical first order decay reactions were observed during the electrolysis carried out under the mass-transport controlled conditions (iappl > ilim). The effects of pH, current density and the initial drug concentration on the kinetics of IF degradation were optimized and properly interpreted. In contrast to the initial IF concentration and current density, the pH effect was of marginal significance.